Research

Research Themes

1. Neurodevelopment and the Endocannabinoid System
   • Investigating the role of the endocannabinoid system in typical and atypical brain development.
   • Examining how endocannabinoid signaling influences critical periods of neurodevelopment, with a focus on fear extinction, emotion regulation, and cognitive functions.
2. Cannabis and Cannabinoid Exposure Across Development
   • Understanding the short- and long-term effects of prenatal, adolescent, and young adult cannabis/cannabinoid exposure on brain structure and function.
   • Identifying vulnerable populations and developmental windows most impacted by cannabis and cannabinoid use.
3. Mental Health and Psychiatric Disorders
   • Exploring the intersection of cannabis use, endocannabinoid system dysregulation, and risk for psychiatric disorders such as anxiety, PTSD, depression, and substance use disorders.
   • Leveraging endocannabinoid system signaling as a biomarker for early detection and intervention in mental health conditions.
4. Prevention and Treatment Interventions
   • Developing and testing behavioral, pharmacological, and integrative therapies targeting the endocannabinoid system to prevent or treat mental health disorders in youth.
   • Utilizing innovative modalities such as mindfulness and exercise alongside cannabinoids to enhance therapeutic outcomes.
5. Community Health and Environmental Impact
   • Investigating the effects of environmental exposures, such as secondhand cannabis smoke, on neurodevelopment and overall health.
   • Collaborating with community partners to design and implement interventions that reduce exposure and promote well-being.

Collaborative Approach

Our research is driven by interdisciplinary collaboration, integrating expertise from neuroscience, psychiatry, adolescent medicine, and public health. We prioritize partnerships with community organizations, healthcare providers, and individuals with lived experiences to ensure that our research is relevant, inclusive, and impactful.

Goals

• Advance the scientific understanding of the endocannabinoid system and its role in mental health and neurodevelopment.
• Inform evidence-based policies and interventions to mitigate risks associated with cannabis and cannabinoid use.
• Promote equitable access to prevention and treatment resources in diverse and underserved populations.
• Foster the next generation of researchers and clinicians through training and mentorship in cannabinoid science.